The Last Unicorn
I don't know if this 1982 movie from Rankin/Bass studios counts as anthro, but surely a talking unicorn would be considered I think. An engaging film based on the Peter S. Beagle novel, the unicorn goes in search of her missing companions. Aided by Shmendrek (hope I spelled his name correctly!) the wizard and his traveling companion Molly Grue, their quest is fraught by many perils. One of the most heart breaking is when the wizard turns the unicorn into a mortal girl to save her from the Red Bull (I can feel this body dying all around me!) If you've seen the movie,you'll know! If you haven't, be sure to give it a watch!